2VHV
Crystal structure of the D270A mutant of L-alanine dehydrogenase from Mycobacterium tuberculosis in complex with NADH.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | ALANINE DEHYDROGENASE | polymer | 377 | 39581.0 | 2 | UniProt (P30234) Pfam (PF05222) Pfam (PF01262) UniProt (by SIFTS) (P9WQB1) | MYCOBACTERIUM TUBERCULOSIS | 40 KDA ANTIGEN, TB43 |
| 2 | C, D (A, B) | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE | non-polymer | 665.4 | 2 | Chemie (NAI) PubChem (928) PubChem (11250888) PubChem (12309341) PubChem (16219774) PubChem (44119956) PubChem (44415182) PubChem (439153) PubChem (124934832) PubChem (126455899) PubChem (134693949) PubChem (12309339) PubChem (12309347) PubChem (140875346) PubChem (162951601) PubChem (162951600) PubChem (164575491) PubChem (169545638) PubChem (170905224) PubChem (174316169) PubChem (94865921) PubChem (94865923) PubChem (124432988) PubChem (124934831) PubChem (124934833) PubChem (129607000) PubChem (129628338) PubChem (146167236) PubChem (162951602) PubChem (174084875) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 17 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 371 (UniProt: P30234)
A, B: 372 - 377 (PDB: 2VHV)
| PDB | External Database | Details |
|---|---|---|
| Asn 270 | Asp 270 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 79162.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1330.9 | |
| All* | Total formula weight | 80492.8 |
