2VHV

Crystal structure of the D270A mutant of L-alanine dehydrogenase from Mycobacterium tuberculosis in complex with NADH.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	ALANINE DEHYDROGENASE	polymer	377	39581.0	2	UniProt (P30234) Pfam (PF05222) Pfam (PF01262) UniProt (by SIFTS) (P9WQB1)	MYCOBACTERIUM TUBERCULOSIS	40 KDA ANTIGEN, TB43
2	C, D (A, B)	1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE	non-polymer		665.4	2	Chemie (NAI)
3	E, F (A, B)	water	water		18.0	17	Chemie (HOH)

Sequence modifications

A, B: 1 - 371 (UniProt: P30234)

PDB	External Database	Details
Asn 270	Asp 270	engineered mutation

A, B: 372 - 377 (PDB: 2VHV)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	79162.0
Non-Polymers*	Number of molecules	2
	Total formula weight	1330.9
All*	Total formula weight	80492.8

*Water molecules are not included.