2VGO

Crystal structure of Aurora B kinase in complex with Reversine inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	SERINE/THREONINE-PROTEIN KINASE 12-A	polymer	284	33537.9	2	UniProt (Q6DE08) Pfam (PF00069) In PDB	XENOPUS LAEVIS (AFRICAN CLAWED FROG)	AURORA B KINASE, AURORA-B-A, AURORA/IPL1-RELATED KINASE 2-A, AIRK2-A
2	C, D	INNER CENTROMERE PROTEIN A	polymer	44	5073.8	2	UniProt (O13024) Pfam (PF03941) In PDB	XENOPUS LAEVIS (AFRICAN CLAWED FROG)	MITOTIC PHOSPHOPROTEIN 130, XL-INCENP
3	A, B	N~6~-cyclohexyl-N~2~-(4-morpholin-4-ylphenyl)-9H-purine-2,6-diamine	non-polymer		393.5	2	Chemie (AD5)
4		water	water		18.0	626	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	77223.3
Non-Polymers*	Number of molecules	2
	Total formula weight	787.0
All*	Total formula weight	78010.2

*Water molecules are not included.