2VEY
CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B IN COMPLEX WITH AN ISOTHIAZOLIDINONE-CONTAINING INHIBITOR
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 1 | polymer | 321 | 37365.6 | 1 | UniProt (P18031) Pfam (PF00102) In PDB | HOMO SAPIENS (HUMAN) | PROTEIN-TYROSINE PHOSPHATASE 1B, PTP-1B, PROTEIN TYROSINE PHOSPHATASE 1B |
| 2 | A | N-{(1S)-2-{4-[(5S)-1,1-dioxido-3-oxoisothiazolidin-5-yl]phenyl}-1-[4-(3-phenylpropyl)-1H-imidazol-2-yl]ethyl}-3-fluorobenzenesulfonamide | non-polymer | 596.7 | 1 | Chemie (IZ5) | |||
| 3 | water | water | 18.0 | 223 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 37365.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 596.7 | |
| All* | Total formula weight | 37962.3 |
