2VEW
CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B IN COMPLEX WITH AN ISOTHIAZOLIDINONE-CONTAINING INHIBITOR
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 1 | polymer | 321 | 37365.6 | 1 | UniProt (P18031) Pfam (PF00102) In PDB | HOMO SAPIENS (HUMAN) | PROTEIN-TYROSINE PHOSPHATASE 1B, PTP-1B, PROTEIN TYROSINE PHOSPHATASE 1B |
| 2 | A | 3-fluoro-N-[(1S)-1-[4-[(2-fluorophenyl)methyl]imidazol-2-yl]-2-[4-[(5S)-1,1,3-trioxo-1,2-thiazolidin-5-yl]phenyl]ethyl]benzenesulfonamide | non-polymer | 584.6 | 1 | Chemie (IZ3) | |||
| 3 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | water | water | 18.0 | 295 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 37365.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 608.9 | |
| All* | Total formula weight | 37974.6 |
