2VDR
Integrin AlphaIIbBeta3 Headpiece Bound to a chimeric Fibrinogen Gamma chain peptide, LGGAKQRGDV
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | INTEGRIN ALPHA-IIB | polymer | 452 | 49030.4 | 1 | UniProt (P08514) Pfam (PF01839) | HOMO SAPIENS (HUMAN) | PLATELET MEMBRANE GLYCOPROTEIN IIB, GPALPHA IIB, GPIIB, INTEGRIN ALPHA-IIB HEAVY CHAIN |
| 2 | B (B) | INTEGRIN BETA-3 | polymer | 461 | 50969.7 | 1 | UniProt (P05106) Pfam (PF17205) Pfam (PF00362) Pfam (PF18372) | HOMO SAPIENS (HUMAN) | PLATELET MEMBRANE GLYCOPROTEIN IIIA, GPIIIA, CD61 ANTIGEN |
| 3 | C (C) | FIBRINOGEN | polymer | 10 | 1002.1 | 1 | UniProt (Q53Y18) UniProt (by SIFTS) (P02679) | HOMO SAPIENS | |
| 4 | D (H) | MONOCLONAL ANTIBODY 10E5 HEAVY CHAIN | polymer | 221 | 23766.5 | 1 | MUS MUSCULUS (MOUSE) | ||
| 5 | E (L) | MONOCLONAL ANTIBODY 10E5 LIGHT CHAIN | polymer | 214 | 23332.7 | 1 | MUS MUSCULUS (MOUSE) | ||
| 6 | F (D) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G21381MC) | |||
| 7 | G (E) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1235.1 | 1 | In PDB GlyTouCan (G09609EN) | |||
| 8 | H, O (A, B) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 9 | I, J, K, L, Q... (A, B) | CALCIUM ION | non-polymer | 40.1 | 6 | Chemie (CA) | |||
| 10 | M, N, S (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
| 11 | P (B) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 12 | T, U, V, W, X (A, B, C, H, L) | water | water | 18.0 | 1142 | Chemie (HOH) |
Sequence modifications
A: 1 - 452 (UniProt: P08514)
C: 402 - 411 (UniProt: Q53Y18)
| PDB | External Database | Details |
|---|---|---|
| Gly 282 | Ala 313 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Arg 408 | Ala 396 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 148101.3 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 2145.9 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1112.6 | |
| All* | Total formula weight | 151359.8 |
