2VD4
Structure of small-molecule inhibitor of Glmu from Haemophilus influenzae reveals an allosteric binding site
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | BIFUNCTIONAL PROTEIN GLMU | polymer | 456 | 49346.1 | 1 | UniProt (P43889) Pfam (PF12804) Pfam (PF00132) | HAEMOPHILUS INFLUENZAE | GLMU FROM HAEMOPHILIS INFLUENZAE |
| 2 | B (A) | 4-chloro-N-(3-methoxypropyl)-N-[(3S)-1-(2-phenylethyl)piperidin-3-yl]benzamide | non-polymer | 415.0 | 1 | Chemie (P21) | |||
| 3 | C, D, E, F, G... (A) | SULFATE ION | non-polymer | 96.1 | 6 | Chemie (SO4) | |||
| 4 | H, I (A) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 2 | Chemie (PG4) | |||
| 5 | J (A) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 1 | Chemie (PGE) | |||
| 6 | K, L (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 7 | N (A) | water | water | 18.0 | 291 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 49346.1 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1578.6 | |
| All* | Total formula weight | 50924.6 |
