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2VCI

4,5 Diaryl Isoxazole Hsp90 Chaperone Inhibitors: Potential Therapeutic Agents for the Treatment of Cancer

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
HEAT SHOCK PROTEIN HSP 90-ALPHApolymer23626601.81UniProt (P07900)
Pfam (PF13589)
HOMO SAPIENS (HUMAN)HSP 86, RENAL CARCINOMA ANTIGEN NY-REN-38
2B
(A)
5-[2,4-DIHYDROXY-5-(1-METHYLETHYL)PHENYL]-N-ETHYL-4-[4-(MORPHOLIN-4-YLMETHYL)PHENYL]ISOXAZOLE-3-CARBOXAMIDEnon-polymer465.51Chemie (2GJ)
3C
(A)
waterwater18.0233Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight26601.8
Non-Polymers*Number of molecules1
Total formula weight465.5
All*Total formula weight27067.3
*Water molecules are not included.

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PDB entries from 2025-07-23

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