2V9J

Crystal structure of the regulatory fragment of mammalian AMPK in complexes with Mg.ATP-AMP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1	polymer	157	17635.8	1	UniProt (P54645) Pfam (PF16579) In PDB	RATTUS NORVEGICUS (RAT)	AMPK ALPHA-1 CHAIN, AMP-ACTIVATED PROTEIN KINASE
2	B	5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2	polymer	87	10040.8	1	UniProt (O43741) Pfam (PF04739) In PDB	HOMO SAPIENS (HUMAN)	AMPK BETA-2 CHAIN, AMP-ACTIVATED PROTEIN KINASE
3	E	5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1	polymer	330	37434.1	1	UniProt (P80385) Pfam (PF00571) In PDB	RATTUS NORVEGICUS (RAT)	AMPK GAMMA-1 CHAIN, AMPKG, AMP-ACTIVATED PROTEIN KINASE
4	E	ADENOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	2	Chemie (ATP)
5	E	ADENOSINE MONOPHOSPHATE	non-polymer		347.2	1	Chemie (AMP)
6	E	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
7		water	water		18.0	142	Chemie (HOH)

Sequence modifications

A: 392 - 395 (PDB: 2V9J)
A: 396 - 548 (UniProt: P54645)
B: 186 - 186 (PDB: 2V9J)
B: 187 - 272 (UniProt: O43741)

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	65110.7
Non-Polymers*	Number of molecules	5
	Total formula weight	1410.2
All*	Total formula weight	66520.9

*Water molecules are not included.