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2V5Z

Structure of human MAO B in complex with the selective inhibitor safinamide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Amine oxidase [flavin-containing] Bpolymer52058837.72UniProt (P27338)
Pfam (PF01593)
Homo sapiens (human)Monoamine oxidase type B,MAO-B
2C, E
(A, B)
FLAVIN-ADENINE DINUCLEOTIDEnon-polymer785.52Chemie (FAD)
3D, F
(A, B)
(S)-(+)-2-[4-(FLUOROBENZYLOXY-BENZYLAMINO)PROPIONAMIDE]non-polymer300.32Chemie (SAG)
4G, H
(A, B)
waterwater18.0717Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight117675.5
Non-Polymers*Number of molecules4
Total formula weight2171.8
All*Total formula weight119847.2
*Water molecules are not included.

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PDB entries from 2025-06-11

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