2V5S

Structural basis for Dscam isoform specificity

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	DSCAM	polymer	394	43562.3	2	UniProt (Q9NBA1) Pfam (PF07679) Pfam (PF13927) UniProt (by SIFTS) (Q0E9H9) In PDB	DROSOPHILA MELANOGASTER (FRUIT FLY)	DOWN SYNDROME CELL ADHESION MOLECULE DSCAM
2	C, D, E, F	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	4	In PDB GlyTouCan (G42666HT)
3		water	water		18.0	246	Chemie (HOH)

Sequence modifications

A, B: 1 - 388 (UniProt: Q9NBA1)

PDB	External Database	Details
Ala -5	-	expression tag
Tyr -4	-	expression tag
Phe -3	-	expression tag
Gln -2	-	expression tag
Gly -1	-	expression tag
Asp 0	-	expression tag
Ile 207	Val 242	variant
Ala 211	Pro 246	variant
Arg 213	Lys 248	variant
Thr 214	Ile 249	variant
Pro 215	Asn 250	variant
Ala 216	Thr 251	variant
Val 218	Thr 253	variant
Gln 219	Tyr 254	variant
Leu 222	Asn 257	variant
Glu 223	Ile 258	variant
Leu 224	Val 259	variant
Met 225	Glu 260	variant
Val 226	Ser 261	variant
Ala 227	Met 262	variant
His 228	Ala 263	variant
Thr 229	Ser 264	variant
Ile 230	Thr 265	variant
Ser 231	Ala 266	variant
Leu 232	Ile 267	variant
Phe 239	Tyr 274	variant

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	87124.5
Branched	Number of molecules	4
	Total formula weight	1697.6
All*	Total formula weight	88822.2

*Water molecules are not included.