2V53

Crystal structure of a SPARC-collagen complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	SPARC	polymer	230	26633.4	1	UniProt (P09486) Pfam (PF09289) Pfam (PF00050) Pfam (PF10591)	HOMO SAPIENS (HUMAN)	SECRETED PROTEIN ACIDIC AND RICH IN CYSTEINE, OSTEONECTIN, ON, BASEMENT-MEMBRANE PROTEIN 40, BM-40
2	B, C, D (B, C, D)	COLLAGEN ALPHA-1(III) CHAIN	polymer	33	3067.3	3	UniProt (P02461) Pfam (PF01391)	HOMO SAPIENS
3	E (E)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
4	F (A)	CALCIUM ION	non-polymer		40.1	1	Chemie (CA)
5	G (D)	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)

Sequence modifications

A: 49 - 52 (PDB: 2V53)
A: 53 - 195 (UniProt: P09486)
A: 204 - 286 (UniProt: P09486)
B, C, D: 1 - 6 (PDB: 2V53)
B, C, D: 28 - 33 (PDB: 2V53)
B, C, D: 7 - 27 (UniProt: P02461)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	35835.4
Branched	Number of molecules	1
	Total formula weight	424.4
Non-Polymers*	Number of molecules	2
	Total formula weight	136.1
All*	Total formula weight	36396.0

*Water molecules are not included.