2V4L
complex of human phosphoinositide 3-kinase catalytic subunit gamma (p110 gamma) with PIK-284
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT GAMMA ISOFORM | polymer | 966 | 110756.2 | 1 | UniProt (P48736) Pfam (PF00794) Pfam (PF00792) Pfam (PF00613) Pfam (PF00454) In PDB | HOMO SAPIENS (HUMAN) | PI3-KINASE P110 SUBUNIT GAMMA, PTDINS-3-KINASE SUBUNIT P110, PI3KGAMMA, P120-PI3K, PI3K, PHOSPHOINOSITIDE 3-KINASE GAMMA |
2 | A | 3-[4-AMINO-1-(1-METHYLETHYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-3-YL]PHENOL | non-polymer | 269.3 | 1 | Chemie (ABJ) | |||
3 | water | water | 18.0 | 50 | Chemie (HOH) |
Sequence modifications
A: 144 - 1102 (UniProt: P48736)
PDB | External Database | Details |
---|---|---|
Met 143 | - | expression tag |
His 1103 | - | expression tag |
His 1104 | - | expression tag |
His 1105 | - | expression tag |
His 1106 | - | expression tag |
His 1107 | - | expression tag |
His 1108 | - | expression tag |
Arg 459 | Gln 459 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 110756.2 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 269.3 | |
All* | Total formula weight | 111025.5 |