2V3E

acid-beta-glucosidase with N-nonyl-deoxynojirimycin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	GLUCOSYLCERAMIDASE	polymer	505	56589.3	2	UniProt (P04062) Pfam (PF02055) Pfam (PF17189)	HOMO SAPIENS (HUMAN)	BETA-GLUCOCEREBROSIDASE, ACID-BETA-GLUCOSIDASE, D-GLUCOSYL-N-ACYLSPHINGOSINE GLUCOHYDROLASE, ALGLUCERASE, IMIGLUCERASE
2	C, D (C, D)	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		732.7	2	In PDB GlyTouCan (G18638YB)
3	E, H (A, B)	(2R,3R,4R,5S)-2-(HYDROXYMETHYL)-1-NONYLPIPERIDINE-3,4,5-TRIOL	non-polymer		289.4	2	Chemie (NND) PubChem (501390) PubChem (501394) PubChem (501395) PubChem (501640) PubChem (3272526) PubChem (9860767) PubChem (25010362) PubChem (124525966) PubChem (59345099) PubChem (70848514) PubChem (70864301) PubChem (70871200) PubChem (93225845) PubChem (95858686) PubChem (95858687) PubChem (124933890) PubChem (124933891) PubChem (155527701) PubChem (163564080)
4	F, I (A, B)	PHOSPHATE ION	non-polymer		95.0	2	Chemie (PO4) PubChem (1061)
5	G (B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)
6	J, K (A, B)	water	water		18.0	1004	Chemie (HOH)

Sequence modifications

A, B: -1 - 0 (PDB: 2V3E)
A, B: 498 - 503 (PDB: 2V3E)
A, B: 1 - 497 (UniProt: P04062)

PDB	External Database	Details
His 495	Arg 534	conflict

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	113178.6
Branched	Number of molecules	2
	Total formula weight	1465.4
Non-Polymers*	Number of molecules	5
	Total formula weight	990.0
All*	Total formula weight	115633.9

*Water molecules are not included.