2V2E
Structure of isoniazid (INH) bound to cytochrome c peroxidase mutant N184R Y36A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | CYTOCHROME C PEROXIDASE | polymer | 294 | 33583.4 | 1 | UniProt (P00431) Pfam (PF00141) | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) | CCP |
| 2 | B (A) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 1 | Chemie (HEM) | |||
| 3 | C (A) | 4-(DIAZENYLCARBONYL)PYRIDINE | non-polymer | 135.1 | 1 | Chemie (ISZ) | |||
| 4 | D (A) | water | water | 18.0 | 315 | Chemie (HOH) |
Sequence modifications
A: 1 - 3 (PDB: 2V2E)
A: 4 - 294 (UniProt: P00431)
A: 4 - 294 (UniProt: P00431)
| PDB | External Database | Details |
|---|---|---|
| Ala 39 | Tyr 106 | engineered mutation |
| Arg 184 | Asn 251 | engineered mutation |
| Asn 210 | Asp 277 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33583.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 751.6 | |
| All* | Total formula weight | 34335.0 |
