2V2E

Structure of isoniazid (INH) bound to cytochrome c peroxidase mutant N184R Y36A

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	CYTOCHROME C PEROXIDASE	polymer	294	33583.4	1	UniProt (P00431) Pfam (PF00141) In PDB	SACCHAROMYCES CEREVISIAE (BAKER'S YEAST)	CCP
2	A	PROTOPORPHYRIN IX CONTAINING FE	non-polymer		616.5	1	Chemie (HEM)
3	A	4-(DIAZENYLCARBONYL)PYRIDINE	non-polymer		135.1	1	Chemie (ISZ)
4		water	water		18.0	315	Chemie (HOH)

Sequence modifications

A: 1 - 3 (PDB: 2V2E)
A: 4 - 294 (UniProt: P00431)

PDB	External Database	Details
Ala 39	Tyr 106	engineered mutation
Arg 184	Asn 251	engineered mutation
Asn 210	Asp 277	conflict

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	33583.4
Non-Polymers*	Number of molecules	2
	Total formula weight	751.6
All*	Total formula weight	34335.0

*Water molecules are not included.