2UZB

Crystal structure of human CDK2 complexed with a thiazolidinone inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	CELL DIVISION PROTEIN KINASE 2	polymer	298	34056.5	2	UniProt (P24941) Pfam (PF00069)	HOMO SAPIENS (HUMAN)	CYCLIN DEPENDENT KINASE 2, P33 PROTEIN KINASE
2	B, D (B, D)	CYCLIN-A2	polymer	258	29624.3	2	UniProt (P20248) Pfam (PF00134) Pfam (PF02984)	HOMO SAPIENS (HUMAN)	CYCLIN A2, CYCLIN-A
3	E, F (A, C)	4-{5-[(Z)-(2-IMINO-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]-2-FURYL}-N-METHYLBENZENESULFONAMIDE	non-polymer		363.4	2	Chemie (C75)
4	G, H, I, J (A, B, C, D)	water	water		18.0	194	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	127361.5
Non-Polymers*	Number of molecules	2
	Total formula weight	726.8
All*	Total formula weight	128088.4

*Water molecules are not included.