2UZ4
HhaI DNA methyltransferase R165N mutant complex with 13mer GCGC-GMGC oligonucleotide and SAH
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | MODIFICATION METHYLASE HHAI | polymer | 327 | 36999.1 | 1 | UniProt (P05102) Pfam (PF00145) | HAEMOPHILUS PARAHAEMOLYTICUS | HHAI DNA METHYLTRANSFERASE, CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI, M.HHAI |
| 2 | B (C) | 5'-D(*TP*GP*GP*AP*TP*GP*5CMP*GP*CP*TP*GP *AP*C)-3' | polymer | 13 | 4021.6 | 1 | DNA OLIGONUCLEOTIDE | ||
| 3 | C (D) | 5'-D(*GP*TP*CP*AP*GP*CP*GP*CP*AP*TP *CP*C)-3' | polymer | 12 | 3623.4 | 1 | DNA OLIGONUCLEOTIDE | ||
| 4 | D (A) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 1 | Chemie (SAH) | |||
| 5 | E, F, G, H (A) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 6 | I, J (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 7 | K, L, M (A, C, D) | water | water | 18.0 | 142 | Chemie (HOH) |
Sequence modifications
A: 1 - 327 (UniProt: P05102)
| PDB | External Database | Details |
|---|---|---|
| Asn 165 | Arg 165 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 44644.1 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 952.9 | |
| All* | Total formula weight | 45597.0 |
