2UXZ
Two-Carbon-Elongated HIV-1 Protease Inhibitors with a Tertiary- Alcohol-Containing Transition-State Mimic
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | HIV-1 PROTEASE | polymer | 99 | 10803.8 | 2 | UniProt (P03366) Pfam (PF00077) | HUMAN IMMUNODEFICIENCY VIRUS 1 | |
| 2 | C (A) | METHYL [(1S)-1-({2-[(4R)-4-BENZYL-4-HYDROXY-5-{[(1S,2R)-2-HYDROXY-2,3-DIHYDRO-1H-INDEN-1-YL]AMINO}-5-OXOPENTYL]-2-(4-BROMOBENZYL)HYDRAZINO}CARBONYL)-2,2-DIMETHYLPROPYL]CARBAMATE | non-polymer | 709.7 | 1 | Chemie (HI1) | |||
| 3 | D, E (A, B) | water | water | 18.0 | 154 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 21607.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 709.7 | |
| All* | Total formula weight | 22317.2 |
