2UXZ

Two-Carbon-Elongated HIV-1 Protease Inhibitors with a Tertiary- Alcohol-Containing Transition-State Mimic

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	HIV-1 PROTEASE	polymer	99	10803.8	2	UniProt (P03366) Pfam (PF00077) In PDB	HUMAN IMMUNODEFICIENCY VIRUS 1
2	A	METHYL [(1S)-1-({2-[(4R)-4-BENZYL-4-HYDROXY-5-{[(1S,2R)-2-HYDROXY-2,3-DIHYDRO-1H-INDEN-1-YL]AMINO}-5-OXOPENTYL]-2-(4-BROMOBENZYL)HYDRAZINO}CARBONYL)-2,2-DIMETHYLPROPYL]CARBAMATE	non-polymer		709.7	1	Chemie (HI1)
3		water	water		18.0	154	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	21607.5
Non-Polymers*	Number of molecules	1
	Total formula weight	709.7
All*	Total formula weight	22317.2

*Water molecules are not included.