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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

2UXC

Crystal structure of an extended tRNA anticodon stem loop in complex with its cognate mRNA UCGU in the context of the Thermus thermophilus 30S subunit.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)		16S RIBOSOMAL RNApolymer1522493958.31THERMUS THERMOPHILUS
2B
(B)		RIBOSOMAL PROTEIN S2polymer25629317.71UniProt (P80371)
Pfam (PF00318)		THERMUS THERMOPHILUS
3C
(C)		RIBOSOMAL PROTEIN S3polymer23926751.11UniProt (P80372)
Pfam (PF07650)
Pfam (PF00189)		THERMUS THERMOPHILUS
4D
(D)		RIBOSOMAL PROTEIN S4polymer20924373.41UniProt (P80373)
Pfam (PF00163)
Pfam (PF01479)		THERMUS THERMOPHILUS
5E
(E)		RIBOSOMAL PROTEIN S5polymer16217583.41UniProt (Q5SHQ5)
Pfam (PF00333)
Pfam (PF03719)		THERMUS THERMOPHILUS
6F
(F)		RIBOSOMAL PROTEIN S6polymer10111988.81UniProt (Q5SLP8)
Pfam (PF01250)		THERMUS THERMOPHILUS
7G
(G)		RIBOSOMAL PROTEIN S7polymer15618051.01UniProt (P17291)
Pfam (PF00177)		THERMUS THERMOPHILUS
8H
(H)		RIBOSOMAL PROTEIN S8polymer13815868.61UniProt (Q5SHQ2)
Pfam (PF00410)
UniProt (by SIFTS) (P0DOY9)		THERMUS THERMOPHILUS
9I
(I)		RIBOSOMAL PROTEIN S9polymer12814429.71UniProt (P80374)
Pfam (PF00380)		THERMUS THERMOPHILUS
10J
(J)		RIBOSOMAL PROTEIN S10polymer10511955.01UniProt (Q5SHN7)
Pfam (PF00338)		THERMUS THERMOPHILUS
11K
(K)		RIBOSOMAL PROTEIN S11polymer12913737.91UniProt (P80376)
Pfam (PF00411)		THERMUS THERMOPHILUS
12L
(L)		RIBOSOMAL PROTEIN S12polymer13514920.81UniProt (Q5SHN3)
Pfam (PF00164)		THERMUS THERMOPHILUS
13M
(M)		RIBOSOMAL PROTEIN S13polymer12614338.91UniProt (P80377)
Pfam (PF00416)		THERMUS THERMOPHILUS
14N
(N)		RIBOSOMAL PROTEIN S14polymer617158.71UniProt (Q5SHQ1)
Pfam (PF00253)
UniProt (by SIFTS) (P0DOY6)		THERMUS THERMOPHILUS
15O
(O)		RIBOSOMAL PROTEIN S15polymer8910578.41UniProt (Q5SJ76)
Pfam (PF00312)		THERMUS THERMOPHILUS
16P
(P)		RIBOSOMAL PROTEIN S16polymer8810410.01UniProt (Q5SJH3)
Pfam (PF00886)		THERMUS THERMOPHILUS
17Q
(Q)		RIBOSOMAL PROTEIN S17polymer10512324.71UniProt (Q5SHP7)
Pfam (PF00366)
UniProt (by SIFTS) (P0DOY7)		THERMUS THERMOPHILUS
18R
(R)		RIBOSOMAL PROTEIN S18polymer8810258.31UniProt (Q5SLQ0)
Pfam (PF01084)		THERMUS THERMOPHILUS
19S
(S)		RIBOSOMAL PROTEIN S19polymer9310605.51UniProt (Q5SHP2)
Pfam (PF00203)		THERMUS THERMOPHILUS
20T
(T)		RIBOSOMAL PROTEIN S20polymer10611722.11UniProt (P80380)
Pfam (PF01649)		THERMUS THERMOPHILUS
21U
(U)		RIBOSOMAL PROTEIN THXpolymer273350.01UniProt (Q5SIH3)
Pfam (PF17070)		THERMUS THERMOPHILUS
22V
(X)		A-SITE MESSENGER RNA FRAGMENT CGGGpolymer185772.51SYNTHETIC CONSTRUCT
23W
(Y)		ANTICODON STEM-LOOP OF TRANSFER RNA WITH ANTICODON ACGApolymer51523.91SYNTHETIC CONSTRUCT
24X
(A)		PAROMOMYCINnon-polymer615.61Chemie (PAR)
PubChem (16757804)
PubChem (16760604)
PubChem (17757254)
PubChem (20849281)
PubChem (71191297)
PubChem (23789070)
PubChem (24096964)
PubChem (24867526)
PubChem (24867858)
PubChem (25104843)
PubChem (44120093)
PubChem (44251565)
PubChem (71188564)
PubChem (53486370)
PubChem (165580)
PubChem (44186758)
PubChem (58160567)
PubChem (44663324)
PubChem (59361026)
PubChem (59800245)
PubChem (45358711)
PubChem (70793652)
PubChem (70793824)
PubChem (70795918)
PubChem (71068776)
PubChem (71072581)
PubChem (71072592)
PubChem (50989619)
PubChem (66932615)
PubChem (68032118)
PubChem (4689)
PubChem (14951)
PubChem (24176)
PubChem (70878598)
PubChem (71751432)
PubChem (73707499)
PubChem (3040200)
PubChem (91151908)
PubChem (91867972)
PubChem (91972181)
PubChem (94469268)
PubChem (98048759)
PubChem (98048761)
PubChem (5702262)
PubChem (121292209)
PubChem (6603975)
PubChem (6604293)
PubChem (122537356)
PubChem (6710686)
PubChem (124226135)
PubChem (124464537)
PubChem (9809147)
PubChem (125040357)
PubChem (125040359)
PubChem (125121197)
PubChem (94469269)
PubChem (94469270)
PubChem (94469271)
PubChem (129009945)
PubChem (131841783)
PubChem (132275078)
PubChem (6602492)
PubChem (6713982)
PubChem (98048758)
PubChem (98048760)
PubChem (101739930)
PubChem (118213779)
PubChem (118705495)
PubChem (9961808)
PubChem (122691713)
PubChem (12313981)
PubChem (124226132)
PubChem (124226133)
PubChem (124226134)
PubChem (124464538)
PubChem (124761786)
PubChem (124761787)
PubChem (124761788)
PubChem (124761789)
PubChem (152952600)
PubChem (125040358)
PubChem (125040360)
PubChem (125121198)
PubChem (162873319)
PubChem (129014632)
PubChem (129014634)
PubChem (129014635)
PubChem (129313238)
PubChem (134771120)
PubChem (137404838)
PubChem (161153506)
PubChem (163199098)
PubChem (164850471)
PubChem (172091638)
PubChem (173719997)
25AA, AB, AC, AD, AE...
(A)		MAGNESIUM IONnon-polymer24.3192Chemie (MG)
PubChem (888)
26AI, BI, CI, DI, EI...
(A)		POTASSIUM IONnon-polymer39.126Chemie (K)
PubChem (813)
27II, JI
(A)		ZINC IONnon-polymer65.42Chemie (ZN)
Sequence modifications
B: 1 - 1 (PDB: 2UXC)
B: 2 - 256 (UniProt: P80371)
C: 1 - 1 (PDB: 2UXC)
C: 2 - 239 (UniProt: P80372)
D: 1 - 1 (PDB: 2UXC)
D: 2 - 209 (UniProt: P80373)
E: 1 - 1 (PDB: 2UXC)
E: 2 - 162 (UniProt: Q5SHQ5)
G: 1 - 1 (PDB: 2UXC)
G: 2 - 156 (UniProt: P17291)
I: 1 - 128 (UniProt: P80374)
PDBExternal DatabaseDetails
Arg 58His 58conflict
J: 1 - 1 (PDB: 2UXC)
J: 2 - 105 (UniProt: Q5SHN7)
K: 1 - 1 (PDB: 2UXC)
K: 2 - 129 (UniProt: P80376)
L: 1 - 4 (PDB: 2UXC)
L: 5 - 135 (UniProt: Q5SHN3)
M: 1 - 1 (PDB: 2UXC)
M: 2 - 126 (UniProt: P80377)
N: 1 - 1 (PDB: 2UXC)
N: 2 - 61 (UniProt: Q5SHQ1)
O: 1 - 1 (PDB: 2UXC)
O: 2 - 89 (UniProt: Q5SJ76)
Q: 1 - 1 (PDB: 2UXC)
Q: 2 - 105 (UniProt: Q5SHP7)
PDBExternal DatabaseDetails
Gln 96Glu 95conflict
R: 1 - 1 (PDB: 2UXC)
R: 2 - 88 (UniProt: Q5SLQ0)
S: 1 - 1 (PDB: 2UXC)
S: 2 - 93 (UniProt: Q5SHP2)
T: 1 - 1 (PDB: 2UXC)
T: 2 - 106 (UniProt: P80380)
PDBExternal DatabaseDetails
Val 41Ile 40conflict
U: 1 - 1 (PDB: 2UXC)
U: 2 - 27 (UniProt: Q5SIH3)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains23
Total formula weight790978.4
Non-Polymers*Number of molecules221
Total formula weight6429.6
All*Total formula weight797408.0
*Water molecules are not included.

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PDB entries from 2026-05-06

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