2UWO
Selective and Dual Action Orally Active Inhibitors of Thrombin and Factor Xa
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | COAGULATION FACTOR X | polymer | 254 | 28550.6 | 1 | UniProt (P00742) Pfam (PF00089) | HOMO SAPIENS (HUMAN) | STUART FACTOR, STUART- PROWER FACTOR, ACTIVATED FACTOR XA HEAVY CHAIN |
| 2 | B (B) | COAGULATION FACTOR X | polymer | 134 | 15210.8 | 1 | UniProt (P00742) Pfam (PF00594) Pfam (PF00008) Pfam (PF14670) | HOMO SAPIENS (HUMAN) | STUART FACTOR, STUART- PROWER FACTOR, ACTIVATED FACTOR XA LIGHT CHAIN |
| 3 | C (A) | (2R)-2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}PROPENE-1-SULFONAMIDE | non-polymer | 462.0 | 1 | Chemie (701) | |||
| 4 | D, E (A, B) | water | water | 18.0 | 203 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 43761.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 462.0 | |
| All* | Total formula weight | 44223.4 |
