2UV7
Crystal Structure of a CBS domain pair from the regulatory gamma1 subunit of human AMPK in complex with AMP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1 | polymer | 152 | 17178.7 | 1 | UniProt (P54619) Pfam (PF00571) | HOMO SAPIENS (HUMAN) | AMPK GAMMA-1 CHAIN, AMPKG, AMPK GAMMA1 CHAIN CBS DOMAINS 3 AND 4 |
| 2 | B (A) | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 1 | Chemie (AMP) | |||
| 3 | C (A) | water | water | 18.0 | 201 | Chemie (HOH) |
Sequence modifications
A: -8 - -1 (PDB: 2UV7)
A: 182 - 325 (UniProt: P54619)
A: 182 - 325 (UniProt: P54619)
| PDB | External Database | Details |
|---|---|---|
| Gly 299 | Arg 299 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 17178.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 347.2 | |
| All* | Total formula weight | 17526.0 |
