2UUH
Crystal structure of Human Leukotriene C4 Synthase in complex with substrate glutathione
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | LEUKOTRIENE C4 SYNTHASE | polymer | 156 | 17411.5 | 1 | UniProt (Q16873) Pfam (PF01124) | HOMO SAPIENS (HUMAN) | LEUKOTRIENE-C(4) SYNTHASE, LTC4 SYNTHASE |
| 2 | B, C (A) | NICKEL (II) ION | non-polymer | 58.7 | 2 | Chemie (NI) | |||
| 3 | D (A) | DODECYL-ALPHA-D-MALTOSIDE | non-polymer | 510.6 | 1 | Chemie (LMU) | |||
| 4 | E (A) | GLUTATHIONE | non-polymer | 307.3 | 1 | Chemie (GSH) | |||
| 5 | F (A) | PALMITOLEIC ACID | non-polymer | 254.4 | 1 | Chemie (PAM) | |||
| 6 | G, H, I, K, L (A) | PALMITIC ACID | non-polymer | 256.4 | 5 | Chemie (PLM) | |||
| 7 | J (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 8 | M (A) | water | water | 18.0 | 122 | Chemie (HOH) |
Sequence modifications
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 17411.5 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 2567.9 | |
| All* | Total formula weight | 19979.5 |
