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2UUC

Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a Valine-ASL with cmo5U in position 34 bound to an mRNA with a GUA-codon in the A-site and paromomycin.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
16S Ribosomal RNApolymer1522493958.31THERMUS THERMOPHILUS
2B
(B)
30S RIBOSOMAL PROTEIN S2polymer25629317.71UniProt (P80371)
Pfam (PF00318)
THERMUS THERMOPHILUS
3C
(C)
30S RIBOSOMAL PROTEIN S3polymer23926751.11UniProt (P80372)
Pfam (PF07650)
Pfam (PF00189)
THERMUS THERMOPHILUS
4D
(D)
30S RIBOSOMAL PROTEIN S4polymer20924373.41UniProt (P80373)
Pfam (PF00163)
Pfam (PF01479)
THERMUS THERMOPHILUS
5E
(E)
30S RIBOSOMAL PROTEIN S5polymer16217583.41UniProt (Q5SHQ5)
Pfam (PF00333)
Pfam (PF03719)
THERMUS THERMOPHILUS
6F
(F)
30S RIBOSOMAL PROTEIN S6polymer10111988.81UniProt (Q5SLP8)
Pfam (PF01250)
THERMUS THERMOPHILUSTS9
7G
(G)
30S RIBOSOMAL PROTEIN S7polymer15618051.01UniProt (P17291)
Pfam (PF00177)
THERMUS THERMOPHILUS
8H
(H)
30S RIBOSOMAL PROTEIN S8polymer13815868.61UniProt (Q5SHQ2)
Pfam (PF00410)
UniProt (by SIFTS) (P0DOY9)
THERMUS THERMOPHILUS
9I
(I)
30S RIBOSOMAL PROTEIN S9polymer12814410.61UniProt (P80374)
Pfam (PF00380)
THERMUS THERMOPHILUS
10J
(J)
30S RIBOSOMAL PROTEIN S10polymer10511955.01UniProt (Q5SHN7)
Pfam (PF00338)
THERMUS THERMOPHILUS
11K
(K)
30S RIBOSOMAL PROTEIN S11polymer12913737.91UniProt (P80376)
Pfam (PF00411)
THERMUS THERMOPHILUS
12L
(L)
30S RIBOSOMAL PROTEIN S12polymer13514920.81UniProt (Q5SHN3)
Pfam (PF00164)
THERMUS THERMOPHILUS
13M
(M)
30S RIBOSOMAL PROTEIN S13polymer12614338.91UniProt (P80377)
Pfam (PF00416)
THERMUS THERMOPHILUS
14N
(N)
30S RIBOSOMAL PROTEIN S14polymer617158.71UniProt (Q5SHQ1)
Pfam (PF00253)
UniProt (by SIFTS) (P0DOY6)
THERMUS THERMOPHILUS
15O
(O)
30S RIBOSOMAL PROTEIN S15polymer8910578.41UniProt (Q5SJ76)
Pfam (PF00312)
THERMUS THERMOPHILUS
16P
(P)
30S RIBOSOMAL PROTEIN S16polymer8810410.01UniProt (Q5SJH3)
Pfam (PF00886)
THERMUS THERMOPHILUS
17Q
(Q)
30S RIBOSOMAL PROTEIN S17polymer10512325.71UniProt (Q5SHP7)
Pfam (PF00366)
UniProt (by SIFTS) (P0DOY7)
THERMUS THERMOPHILUS
18R
(R)
30S RIBOSOMAL PROTEIN S18polymer8810258.31UniProt (Q5SLQ0)
Pfam (PF01084)
THERMUS THERMOPHILUS
19S
(S)
30S RIBOSOMAL PROTEIN S19polymer9310605.51UniProt (Q5SHP2)
Pfam (PF00203)
THERMUS THERMOPHILUS
20T
(T)
30S RIBOSOMAL PROTEIN S20polymer10611736.11UniProt (P80380)
Pfam (PF01649)
THERMUS THERMOPHILUS
21U
(U)
30S RIBOSOMAL PROTEIN THXpolymer273350.01UniProt (Q5SIH3)
Pfam (PF17070)
THERMUS THERMOPHILUS
22V
(X)
5'-R(*GP*UP*AP*AP*AP*AP)-3'polymer61923.21synthetic constructRNA
23W
(Y)
5'-R(*CP*CP*UP*CP*CP*CP*UP*CM0P*AP*CP*6MZP*AP *GP*GP*AP*GP*G)-3'polymer175490.31RNA
24X
(A)
PAROMOMYCINnon-polymer615.61Chemie (PAR)
25AA, AB, AC, AD, AE...
(A, K, M, N, Q...)
MAGNESIUM IONnon-polymer24.3184Chemie (MG)
26AH, AI, BH, BI, CH...
(A, Q, E, G)
POTASSIUM IONnon-polymer39.156Chemie (K)
27CJ, SI
(N, D)
ZINC IONnon-polymer65.42Chemie (ZN)
Sequence modifications
B: 1 - 1 (PDB: 2UUC)
B: 2 - 256 (UniProt: P80371)
C: 1 - 1 (PDB: 2UUC)
C: 2 - 239 (UniProt: P80372)
D: 1 - 1 (PDB: 2UUC)
D: 2 - 209 (UniProt: P80373)
E: 1 - 1 (PDB: 2UUC)
E: 2 - 162 (UniProt: Q5SHQ5)
G: 1 - 1 (PDB: 2UUC)
G: 2 - 156 (UniProt: P17291)
J: 1 - 1 (PDB: 2UUC)
J: 2 - 105 (UniProt: Q5SHN7)
K: 1 - 1 (PDB: 2UUC)
K: 2 - 129 (UniProt: P80376)
L: 1 - 4 (PDB: 2UUC)
L: 5 - 135 (UniProt: Q5SHN3)
M: 1 - 1 (PDB: 2UUC)
M: 2 - 126 (UniProt: P80377)
N: 1 - 1 (PDB: 2UUC)
N: 2 - 61 (UniProt: Q5SHQ1)
O: 1 - 1 (PDB: 2UUC)
O: 2 - 89 (UniProt: Q5SJ76)
Q: 1 - 1 (PDB: 2UUC)
Q: 2 - 105 (UniProt: Q5SHP7)
R: 1 - 1 (PDB: 2UUC)
R: 2 - 88 (UniProt: Q5SLQ0)
S: 1 - 1 (PDB: 2UUC)
S: 2 - 93 (UniProt: Q5SHP2)
T: 1 - 1 (PDB: 2UUC)
T: 2 - 106 (UniProt: P80380)
U: 1 - 1 (PDB: 2UUC)
U: 2 - 27 (UniProt: Q5SIH3)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains23
Total formula weight791091.6
Non-Polymers*Number of molecules243
Total formula weight7408.1
All*Total formula weight798499.6
*Water molecules are not included.

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PDB entries from 2025-06-11

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