2TUN
CONFORMATIONAL CHANGES IN THE (ALA-84-VAL) MUTANT OF TUMOR NECROSIS FACTOR
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | TUMOR NECROSIS FACTOR-ALPHA | polymer | 157 | 17396.8 | 6 | UniProt (P01375) Pfam (PF00229) | Homo sapiens (human) |
Sequence modifications
A, B, C, D, E, F: 1 - 157 (UniProt: P01375)
| PDB | External Database | Details |
|---|---|---|
| Val 84 | Ala 160 | engineered mutation |
| Leu 143 | Asp 219 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 104380.7 | |
| All* | Total formula weight | 104380.7 |
