2RQ8

Solution NMR structure of titin I27 domain mutant

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Titin	polymer	98	10930.5	1	UniProt (Q8WZ42) In PDB	Homo sapiens (Human)	Connectin, Rhabdomyosarcoma antigen MU-RMS-40.14

Sequence modifications

A: 1 - 89 (UniProt: Q8WZ42)

PDB	External Database	Details
Met 0	-	expression tag
Glu 3	Lys 12679	engineered mutation
Pro 9	Tyr 12685	engineered mutation
Ala 42	Thr 12718	engineered mutation
Thr 78	Ala 12754	engineered mutation
Leu 90	-	expression tag
Glu 91	-	expression tag
His 92	-	expression tag
His 93	-	expression tag
His 94	-	expression tag
His 95	-	expression tag
His 96	-	expression tag
His 97	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	10930.5
All*	Total formula weight	10930.5

*Water molecules are not included.