2RL7
Crystal Structure cation-dependent mannose 6-phosphate receptor at pH 4.8
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Cation-dependent mannose-6-phosphate receptor | polymer | 154 | 17443.6 | 4 | UniProt (P11456) Pfam (PF02157) | Bos taurus (cattle) | CD Man-6-P receptor, CD-MPR, 46 kDa mannose 6-phosphate receptor, MPR 46 |
| 2 | E, F, G, H (E, F, G, H) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 4 | In PDB GlyTouCan (G42666HT) | |||
| 3 | I, O (A, C) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 4 | J, K, M, N, P (B, C, D) | ACETATE ION | non-polymer | 59.0 | 5 | Chemie (ACT) | |||
| 5 | L (B) | CACODYLATE ION | non-polymer | 137.0 | 1 | Chemie (CAC) | |||
| 6 | Q, R, S, T (A, B, C, D) | water | water | 18.0 | 482 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 154 (UniProt: P11456)
| PDB | External Database | Details |
|---|---|---|
| Gln 31 | Asn 59 | engineered mutation |
| Gln 57 | Asn 85 | engineered mutation |
| Gln 68 | Asn 96 | engineered mutation |
| Gln 87 | Asn 115 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 69774.3 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 1697.6 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 616.4 | |
| All* | Total formula weight | 72088.3 |
