2RIV

Crystal structure of the reactive loop cleaved human Thyroxine Binding Globulin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Thyroxine-binding globulin	polymer	343	38399.1	1	UniProt (P05543) Pfam (PF00079)	Homo sapiens (human)	TBG, T4-binding globulin, Serpin A7
2	B (B)	Thyroxine-binding globulin	polymer	40	4605.4	1	UniProt (P05543)	Homo sapiens (human)	TBG, T4-binding globulin, Serpin A7
3	C, D, E (A)	GLYCEROL	non-polymer		92.1	3	Chemie (GOL)
4	F, G (A)	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
5	H, I (A, B)	water	water		18.0	428	Chemie (HOH)

Sequence modifications

A: 13 - 355 (UniProt: P05543)

PDB	External Database	Details
Gly 346	Ala 366	SEE REMARK 999
Ala 347	Val 367	SEE REMARK 999
Met 348	Pro 368	SEE REMARK 999
Phe 349	Glu 369	SEE REMARK 999
Leu 350	Val 370	SEE REMARK 999
Glu 351	Glu 371	SEE REMARK 999
Ala 352	Leu 372	SEE REMARK 999
Ile 353	Ser 373	SEE REMARK 999
Pro 354	Asp 374	SEE REMARK 999
Arg 355	Gln 375	SEE REMARK 999

B: 356 - 395 (UniProt: P05543)

PDB	External Database	Details
Ser 356	Pro 376	SEE REMARK 999

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	43004.5
Non-Polymers*	Number of molecules	5
	Total formula weight	468.4
All*	Total formula weight	43472.9

*Water molecules are not included.