2RHU

Crystal structure of the 3-MBT repeats from human L3MBTL1 bound to dimethyl-lysine and in chimera with histone H3.3(28-34)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Lethal(3)malignant brain tumor-like protein	polymer	329	37422.7	1	UniProt (Q9Y468) Pfam (PF02820) In PDB	Homo sapiens (human)	L3, mbt-like, L3, mbt protein homolog, H-l3, mbt protein, H-L3, MBT, L3MBTL1
2	A	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
3	A	N-DIMETHYL-LYSINE	non-polymer		174.2	1	Chemie (MLY)
4	A	TETRAETHYLENE GLYCOL	non-polymer		194.2	1	Chemie (PG4)
5	A	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	1	Chemie (PEG)
6		water	water		18.0	522	Chemie (HOH)

Sequence modifications

A: 206 - 519 (UniProt: Q9Y468)

PDB	External Database	Details
Gly 201	-	expression tag
Pro 202	-	expression tag
Leu 203	-	expression tag
Gly 204	-	expression tag
Ser 205	-	expression tag
Gly 520	-	linker
Gly 521	-	linker
Gly 522	-	linker
Ser 523	-	SEE REMARK 999
Ala 524	-	SEE REMARK 999
Pro 525	-	SEE REMARK 999
Ser 526	-	SEE REMARK 999
Thr 527	-	SEE REMARK 999
Gly 528	-	SEE REMARK 999
Gly 529	-	SEE REMARK 999

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	37422.7
Non-Polymers*	Number of molecules	4
	Total formula weight	570.7
All*	Total formula weight	37993.3

*Water molecules are not included.