2RHU
Crystal structure of the 3-MBT repeats from human L3MBTL1 bound to dimethyl-lysine and in chimera with histone H3.3(28-34)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Lethal(3)malignant brain tumor-like protein | polymer | 329 | 37422.7 | 1 | UniProt (Q9Y468) Pfam (PF02820) | Homo sapiens (human) | L3, mbt-like, L3, mbt protein homolog, H-l3, mbt protein, H-L3, MBT, L3MBTL1 |
| 2 | B (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 3 | C (A) | N-DIMETHYL-LYSINE | non-polymer | 174.2 | 1 | Chemie (MLY) | |||
| 4 | D (A) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
| 5 | E (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 6 | F (A) | water | water | 18.0 | 522 | Chemie (HOH) |
Sequence modifications
A: 206 - 519 (UniProt: Q9Y468)
| PDB | External Database | Details |
|---|---|---|
| Gly 201 | - | expression tag |
| Pro 202 | - | expression tag |
| Leu 203 | - | expression tag |
| Gly 204 | - | expression tag |
| Ser 205 | - | expression tag |
| Gly 520 | - | linker |
| Gly 521 | - | linker |
| Gly 522 | - | linker |
| Ser 523 | - | SEE REMARK 999 |
| Ala 524 | - | SEE REMARK 999 |
| Pro 525 | - | SEE REMARK 999 |
| Ser 526 | - | SEE REMARK 999 |
| Thr 527 | - | SEE REMARK 999 |
| Gly 528 | - | SEE REMARK 999 |
| Gly 529 | - | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 37422.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 570.7 | |
| All* | Total formula weight | 37993.3 |
