2RHI
Crystal structure of the 3-MBT domain from human L3MBTL1 in complex with H1.5K27me2 at 1.66 angstrom
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Lethal(3)malignant brain tumor-like protein | polymer | 345 | 39195.7 | 1 | UniProt (Q9Y468) Pfam (PF02820) | Homo sapiens (human) | L3, mbt-like, L3, mbt protein homolog, H-l3, mbt protein, H-L3, MBT, L3MBTL1 |
| 2 | B (B) | Histone H1.5 | polymer | 5 | 604.8 | 1 | UniProt (P16401) | ||
| 3 | C (A) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
| 4 | D (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 5 | E, F (A, B) | water | water | 18.0 | 564 | Chemie (HOH) |
Sequence modifications
A: 197 - 526 (UniProt: Q9Y468)
| PDB | External Database | Details |
|---|---|---|
| Gly 192 | - | expression tag |
| Ser 193 | - | expression tag |
| Pro 194 | - | expression tag |
| Asn 195 | - | expression tag |
| Ser 196 | - | expression tag |
| Val 527 | - | expression tag |
| Asp 528 | - | expression tag |
| Ser 529 | - | expression tag |
| Ser 530 | - | expression tag |
| Gly 531 | - | expression tag |
| Arg 532 | - | expression tag |
| Ile 533 | - | expression tag |
| Val 534 | - | expression tag |
| Thr 535 | - | expression tag |
| Asp 536 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 39800.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 300.3 | |
| All* | Total formula weight | 40100.9 |
