2RB8

High resolution design of a protein loop

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Tenascin	polymer	104	11617.8	1	UniProt (P24821) Pfam (PF00041) In PDB	Homo sapiens (human)	TN, Tenascin-C, TN-C, Hexabrachion, Cytotactin, Neuronectin, GMEM, JI, Myotendinous antigen, Glioma- associated-extracellular matrix antigen, GP 150-225
2		water	water		18.0	78	Chemie (HOH)

Sequence modifications

A: 802 - 893 (UniProt: P24821)

PDB	External Database	Details
Met 801	-	initiating methionine
Met 824	Phe 824	engineered mutation
Pro 825	Lys 825	engineered mutation
Ser 827	Leu 827	engineered mutation
Gln 828	Ala 828	engineered mutation
Pro 829	Glu 829	engineered mutation
Val 830	Ile 830	engineered mutation
Phe 833	Ile 833	engineered mutation
Ala 894	-	expression tag
Ala 895	-	expression tag
Ala 896	-	expression tag
Leu 897	-	expression tag
Glu 898	-	expression tag
His 899	-	expression tag
His 900	-	expression tag
His 901	-	expression tag
His 902	-	expression tag
His 903	-	expression tag
His 904	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	11617.8
All*	Total formula weight	11617.8

*Water molecules are not included.