2R0O
Crystal structure of the actin-binding domain of human alpha-actinin-4 mutant(K255E)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Alpha-actinin-4 | polymer | 237 | 27128.1 | 2 | UniProt (O43707) Pfam (PF00307) In PDB | Homo sapiens (human) | Non-muscle alpha-actinin 4, F-actin cross-linking protein |
2 | A, B | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | Non-muscle alpha-actinin 4, F-actin cross-linking protein | ||
3 | water | water | 18.0 | 457 | Chemie (HOH) |
Sequence modifications
A, B: 47 - 271 (UniProt: O43707)
PDB | External Database | Details |
---|---|---|
Gly 40 | - | expression tag |
Ala 41 | - | expression tag |
Met 42 | - | expression tag |
Asp 43 | - | expression tag |
Pro 44 | - | expression tag |
Glu 45 | - | expression tag |
Phe 46 | - | expression tag |
Glu 255 | Lys 255 | engineered mutation |
Leu 272 | - | expression tag |
Asp 273 | - | expression tag |
Glu 274 | - | expression tag |
Leu 275 | - | expression tag |
Asn 276 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 54256.1 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 368.4 | |
All* | Total formula weight | 54624.5 |