2QYN
Crystal structure of PDE4D2 in complex with inhibitor NPV
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | polymer | 328 | 37793.8 | 2 | UniProt (Q08499) Pfam (PF00233) | Homo sapiens (human) | DPDE3, PDE43 |
| 2 | C, F (A, B) | 4-[8-(3-nitrophenyl)-1,7-naphthyridin-6-yl]benzoic acid | non-polymer | 371.3 | 2 | Chemie (NPV) | |||
| 3 | D, G (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | E, H (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 365 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 75587.6 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 922.1 | |
| All* | Total formula weight | 76509.7 |
