2QUH

Crystal structures of human tryptophanyl-tRNA synthetase in complex with Trp

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Tryptophanyl-tRNA synthetase	polymer	477	54060.1	2	UniProt (P23381) Pfam (PF00458) Pfam (PF00579)	Homo sapiens (human)	Tryptophan-tRNA ligase, TrpRS, Interferon-induced protein 53, IFP53, hWRS
2	C, D (B)	TRYPTOPHAN	non-polymer		204.2	2	Chemie (TRP)
3	E, F (A, B)	water	water		18.0	278	Chemie (HOH)

Sequence modifications

A, B: 1 - 471 (UniProt: P23381)

PDB	External Database	Details
His 472	-	expression tag
His 473	-	expression tag
His 474	-	expression tag
His 475	-	expression tag
His 476	-	expression tag
His 477	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	108120.2
Non-Polymers*	Number of molecules	2
	Total formula weight	408.4
All*	Total formula weight	108528.7

*Water molecules are not included.