2QTZ
Crystal Structure of the NADP+-bound FAD-containing FNR-like Module of Human Methionine Synthase Reductase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Methionine synthase reductase | polymer | 539 | 60056.5 | 1 | UniProt (Q9UBK8) Pfam (PF00667) Pfam (PF00175) | Homo sapiens (human) | Methionine synthase reductase, mitochondrial; MSR |
| 2 | B (A) | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 1 | Chemie (FAD) | |||
| 3 | C (A) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 1 | Chemie (NAP) | |||
| 4 | D (A) | water | water | 18.0 | 352 | Chemie (HOH) |
Sequence modifications
A: 165 - 698 (UniProt: Q9UBK8)
| PDB | External Database | Details |
|---|---|---|
| Gly 160 | - | expression tag |
| Ser 161 | - | expression tag |
| Pro 162 | - | expression tag |
| Glu 163 | - | expression tag |
| Phe 164 | - | expression tag |
| Phe 523 | Ser 550 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 60056.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1529.0 | |
| All* | Total formula weight | 61585.5 |
