2QTW
The Crystal Structure of PCSK9 at 1.9 Angstroms Resolution Reveals structural homology to Resistin within the C-terminal domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Proprotein convertase subtilisin/kexin type 9 Propeptide | polymer | 124 | 14019.7 | 1 | UniProt (Q8NBP7) Pfam (PF05922) | Homo sapiens (human) | Proprotein convertase PC9, Subtilisin/kexin-like protease PC9, Neural apoptosis-regulated convertase 1, NARC-1 |
| 2 | B (B) | Proprotein convertase subtilisin/kexin type 9 | polymer | 546 | 58272.6 | 1 | UniProt (Q8NBP7) Pfam (PF00082) Pfam (PF18459) Pfam (PF18464) Pfam (PF18463) | Homo sapiens (human) | Proprotein convertase PC9, Subtilisin/kexin-like protease PC9, Neural apoptosis-regulated convertase 1, NARC-1 |
| 3 | C (B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 4 | D (B) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 5 | E, F (A, B) | water | water | 18.0 | 320 | Chemie (HOH) |
Sequence modifications
B: 153 - 692 (UniProt: Q8NBP7)
| PDB | External Database | Details |
|---|---|---|
| His 693 | - | expression tag |
| His 694 | - | expression tag |
| His 695 | - | expression tag |
| His 696 | - | expression tag |
| His 697 | - | expression tag |
| His 698 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 72292.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 261.3 | |
| All* | Total formula weight | 72553.6 |
