2QTU

Estrogen receptor beta ligand-binding domain complexed to a benzopyran ligand

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Estrogen receptor beta	polymer	257	29228.6	2	UniProt (Q92731) Pfam (PF00104)	Homo sapiens (human)	ER-beta
2	C, D (A, B)	(3aS,4R,9bR)-2,2-difluoro-4-(4-hydroxyphenyl)-6-(methoxymethyl)-1,2,3,3a,4,9b-hexahydrocyclopenta[c]chromen-8-ol	non-polymer		362.4	2	Chemie (3AS)
3	E (A)	water	water		18.0	2	Chemie (HOH)

Sequence modifications

A, B: 256 - 505 (UniProt: Q92731)

PDB	External Database	Details
Met 249	-	expression tag
His 250	-	expression tag
His 251	-	expression tag
His 252	-	expression tag
His 253	-	expression tag
His 254	-	expression tag
His 255	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	58457.3
Non-Polymers*	Number of molecules	2
	Total formula weight	724.7
All*	Total formula weight	59182.0

*Water molecules are not included.