2QSE
Crystal Structure of the Estrogen Receptor Alpha Ligand Binding Domain complexed with Burned Meat Compound 4-OH-PhIP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Estrogen receptor | polymer | 258 | 29386.6 | 2 | UniProt (P03372) Pfam (PF00104) In PDB | Homo sapiens (human) | ER, Estradiol receptor, ER-alpha |
| 2 | C, D | Nuclear receptor coactivator 2 | polymer | 13 | 1579.9 | 2 | UniProt (Q8BN74) UniProt (by SIFTS) (Q61026) In PDB | Mus Musculus | |
| 3 | A, B | 4-(2-amino-1-methyl-1H-imidazo[4,5-b]pyridin-6-yl)phenol | non-polymer | 240.3 | 2 | Chemie (1HP) | |||
| 4 | water | water | 18.0 | 359 | Chemie (HOH) |
Sequence modifications
A, B: 298 - 554 (UniProt: P03372)
| PDB | External Database | Details |
|---|---|---|
| Ser 297 | - | expression tag |
| Ser 537 | Tyr 537 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 61932.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 480.5 | |
| All* | Total formula weight | 62413.5 |
