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2QOI

Human EphA3 kinase and juxtamembrane region, Y596F:Y602F double mutant

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Ephrin receptorpolymer37341931.91UniProt (Q6P4R6)
Pfam (PF14575)
Pfam (PF07714)
Pfam (PF07647)
UniProt (by SIFTS) (P29320)
Homo sapiens (human)
2B
(A)
BETA-MERCAPTOETHANOLnon-polymer78.11Chemie (BME)
3C
(A)
waterwater18.0357Chemie (HOH)
Sequence modifications
A: 577 - 947 (UniProt: Q6P4R6)
PDBExternal DatabaseDetails
Gly 575-expression tag
Ser 576-expression tag
Phe 596Tyr 596engineered mutation
Phe 602Tyr 602engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight41931.9
Non-Polymers*Number of molecules1
Total formula weight78.1
All*Total formula weight42010.0
*Water molecules are not included.

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PDB entries from 2024-11-06

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