2QMC

Crystal Structure of Helicobacter Pylori Gamma-Glutamyltranspeptidase T380A Mutant

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	Gamma-glutamyltranspeptidase	polymer	377	40577.4	2	UniProt (O25743) Pfam (PF01019)	Helicobacter pylori	Ggt
2	B, D (B, D)	Gamma-glutamyltranspeptidase	polymer	188	20380.2	2	UniProt (O25743) Pfam (PF01019)	Helicobacter pylori	Ggt
3	E, F (B, D)	S-(P-NITROBENZYL)GLUTATHIONE	non-polymer		442.4	2	Chemie (GTB)
4	G, H, I, J (A, B, C, D)	water	water		18.0	588	Chemie (HOH)

Sequence modifications

A, C: 25 - 379 (UniProt: O25743)

PDB	External Database	Details
Met 3	-	expression tag
Gly 4	-	expression tag
Ser 5	-	expression tag
Ser 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
His 9	-	expression tag
His 10	-	expression tag
His 11	-	expression tag
His 12	-	expression tag
Ser 13	-	expression tag
Ser 14	-	expression tag
Gly 15	-	expression tag
Leu 16	-	expression tag
Val 17	-	expression tag
Pro 18	-	expression tag
Arg 19	-	expression tag
Gly 20	-	expression tag
Ser 21	-	expression tag
His 22	-	expression tag
Met 23	-	expression tag
Ala 24	-	expression tag

B, D: 380 - 567 (UniProt: O25743)

PDB	External Database	Details
Ala 380	Thr 380	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	121915.1
Non-Polymers*	Number of molecules	2
	Total formula weight	884.9
All*	Total formula weight	122800.0

*Water molecules are not included.