2QKS

Crystal structure of a Kir3.1-prokaryotic Kir channel chimera

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Kir3.1-prokaryotic Kir channel chimera	polymer	321	36176.6	2	UniProt (P63250) UniProt (Q146M9) Pfam (PF01007) Pfam (PF07885) Pfam (PF17655)	Mus musculus (Mouse)	GIRK1, Potassium channel, inwardly rectifying subfamily J member 3, Inward rectifier K+, channel Kir3.1
2	C (A)	nonyl beta-D-glucopyranoside	non-polymer		306.4	1	Chemie (BNG)
3	D, E, F, G, H... (A, B)	POTASSIUM ION	non-polymer		39.1	12	Chemie (K)
4	P, Q (A, B)	water	water		18.0	226	Chemie (HOH)

Sequence modifications

A, B: 3 - 44 (UniProt: P63250)

PDB	External Database	Details
Gly 1	-	expression tag
Ser 2	-	expression tag

A, B: 45 - 124 (UniProt: Q146M9)
A, B: 125 - 318 (UniProt: P63250)

PDB	External Database	Details
Ala 127	Met 180	engineered mutation
Val 319	-	expression tag
Pro 320	-	expression tag
Arg 321	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	72353.2
Non-Polymers*	Number of molecules	13
	Total formula weight	775.6
All*	Total formula weight	73128.7

*Water molecules are not included.