2QK7

A covalent S-F heterodimer of staphylococcal gamma-hemolysin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Gamma-hemolysin component A	polymer	288	32725.8	1	UniProt (P0A074) Pfam (PF07968) In PDB	Staphylococcus aureus subsp. aureus	H-gamma-2, H-gamma-II
2	B	Gamma-hemolysin component B	polymer	307	34880.6	1	UniProt (P0A077) Pfam (PF07968) UniProt (by SIFTS) (Q57227) In PDB	Staphylococcus aureus subsp. aureus	H-gamma-1, H-gamma-I
3		water	water		18.0	173	Chemie (HOH)

Sequence modifications

A: 1 - 280 (UniProt: P0A074)

PDB	External Database	Details
Gly -7	-	expression tag
Pro -6	-	expression tag
Leu -5	-	expression tag
Gly -4	-	expression tag
Ser -3	-	expression tag
Pro -2	-	expression tag
Glu -1	-	expression tag
Phe 0	-	expression tag
Cys 28	Thr 57	engineered mutation
Lys 217	Arg 246	SEE REMARK 999

B: 1 - 299 (UniProt: P0A077)

PDB	External Database	Details
Gly -7	-	expression tag
Pro -6	-	expression tag
Leu -5	-	expression tag
Gly -4	-	expression tag
Ser -3	-	expression tag
Pro -2	-	expression tag
Glu -1	-	expression tag
Phe 0	-	expression tag
Ala 56	Thr 82	SEE REMARK 999
Tyr 63	Phe 89	SEE REMARK 999
Glu 64	Val 90	SEE REMARK 999
Cys 156	Asn 182	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	67606.4
All*	Total formula weight	67606.4

*Water molecules are not included.