2QEL

Crystal structure of the highly amyloidogenic transthyretin mutant TTR G53S/E54D/L55S- heated protein

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Transthyretin	polymer	127	13767.3	4	UniProt (P02766) Pfam (PF00576)	Homo sapiens (human)	Prealbumin, TBPA, TTR, ATTR
2	E, F, G, H (A, B, C, D)	water	water		18.0	150	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 127 (UniProt: P02766)

PDB	External Database	Details
Ser 53	Gly 73	engineered mutation
Asp 54	Glu 74	engineered mutation
Ser 55	Leu 75	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	55069.1
All*	Total formula weight	55069.1

*Water molecules are not included.