2QDP

Crystal structure of the HePTP catalytic domain C270S mutant crystallized in ammonium acetate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Tyrosine-protein phosphatase non-receptor type 7	polymer	309	35319.9	1	UniProt (P35236) Pfam (PF00102) In PDB	Homo sapiens (human)	Protein-tyrosine phosphatase LC-PTP, Hematopoietic protein-tyrosine phosphatase, HEPTP
2	A	PHOSPHATE ION	non-polymer		95.0	1	Chemie (PO4)
3		water	water		18.0	132	Chemie (HOH)

Sequence modifications

A: 44 - 339 (UniProt: P35236)

PDB	External Database	Details
Met -12	-	expression tag
Gly -11	-	expression tag
Ser -10	-	expression tag
Asp -9	-	expression tag
Lys -8	-	expression tag
Ile -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
Met 0	-	expression tag
Ser 270	Cys 291	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	35319.9
Non-Polymers*	Number of molecules	1
	Total formula weight	95.0
All*	Total formula weight	35414.9

*Water molecules are not included.