2QDH

Fructose-1,6-bisphosphate aldolase from Leishmania mexicana in complex with mannitol-1,6-bisphosphate, a competitive inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Fructose-1,6-bisphosphate aldolase	polymer	391	43058.1	4	UniProt (Q9U5N6)	Leishmania mexicana
2	E, F, G, H (A, B, C, D)	D-MANNITOL-1,6-DIPHOSPHATE	non-polymer		342.1	4	Chemie (M2P)
3	I, J, K, L (A, B, C, D)	water	water		18.0	1730	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 371 (UniProt: Q9U5N6)

PDB	External Database	Details
Met -19	-	expression tag
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	172232.2
Non-Polymers*	Number of molecules	4
	Total formula weight	1368.5
All*	Total formula weight	173600.8

*Water molecules are not included.