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2QAD

Structure of tyrosine-sulfated 412d antibody complexed with HIV-1 YU2 gp120 and CD4

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, E
(A, E)
Envelope glycoprotein gp160polymer32236062.12UniProt (P35961)
Pfam (PF00516)
Human immunodeficiency virus 1Env polyprotein
2B, F
(B, F)
T-cell surface glycoprotein CD4polymer18120129.92UniProt (P01730)
Pfam (PF00047)
Pfam (PF05790)
Homo sapiens (human)T-cell surface antigen T4/Leu-3
3C, G
(C, G)
anti-HIV-1 antibody 412d light chainpolymer21423483.12UniProt (Q6GMX8)Homo sapiens (human)
4D, H
(D, H)
anti-HIV-1 antibody 412d heavy chainpolymer23124839.72UniProt (A4F255)
Pfam (PF07686)
Pfam (PF07654)
Homo sapiens (human)
5EA, FA, GA, HA, I...
(E, A)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.231Chemie (NAG)
6AA, VA, XA, Y
(B, F, H, A)
MALONIC ACIDnon-polymer104.14Chemie (MLA)
7BA, CA, DA, TA, UA...
(C, D, E, F, A)
1,2-ETHANEDIOLnon-polymer62.17Chemie (EDO)
Sequence modifications
A, E: 89 - 121 (UniProt: P35961)
A, E: 199 - 492 (UniProt: P35961)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight209029.4
Non-Polymers*Number of molecules42
Total formula weight7708.2
All*Total formula weight216737.6
*Water molecules are not included.

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PDB entries from 2025-06-18

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