2Q8Z

Crystal structure of Plasmodium falciparum orotidine 5'-phosphate decarboxylase complexed with 6-amino-UMP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Orotidine-monophosphate-decarboxylase	polymer	342	39899.5	2	UniProt (Q8IJH3) Pfam (PF00215)	Plasmodium falciparum
2	C, G (A, B)	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
3	D, H (A, B)	6-AMINOURIDINE 5'-MONOPHOSPHATE	non-polymer		339.2	2	Chemie (NUP)
4	E (A)	2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL	non-polymer		310.4	1	Chemie (7PE)
5	F, I (A, B)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	2	Chemie (PEG)
6	J, K (A, B)	water	water		18.0	257	Chemie (HOH)

Sequence modifications

A, B: 1 - 323 (UniProt: Q8IJH3)

PDB	External Database	Details
Met -18	-	expression tag
Gly -17	-	expression tag
Ser -16	-	expression tag
Ser -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
Ser -8	-	expression tag
Ser -7	-	expression tag
Gly -6	-	expression tag
Leu -5	-	expression tag
Val -4	-	expression tag
Pro -3	-	expression tag
Arg -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	79798.9
Non-Polymers*	Number of molecules	7
	Total formula weight	1393.1
All*	Total formula weight	81192.1

*Water molecules are not included.