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2Q8S

X-ray Crystal structure of the nuclear hormone receptor PPAR-gamma in a complex with a PPAR gamma/alpha dual agonist

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Peroxisome proliferator-activated receptor gammapolymer27130997.02UniProt (P37231)
Pfam (PF00104)
Homo sapiens (human)PPAR-gamma
2C
(A)
(2S)-3-{4-[3-(5-METHYL-2-PHENYL-1,3-OXAZOL-4-YL)PROPYL]PHENYL}-2-(1H-PYRROL-1-YL)PROPANOIC ACIDnon-polymer414.51Chemie (L92)
3D, E
(A, B)
waterwater18.059Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight61994.0
Non-Polymers*Number of molecules1
Total formula weight414.5
All*Total formula weight62408.5
*Water molecules are not included.

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PDB entries from 2025-06-11

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