2Q7H
Pyrrolysyl-tRNA synthetase bound to adenylated pyrrolysine and pyrophosphate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Pyrrolysyl-tRNA synthetase | polymer | 291 | 33416.2 | 1 | UniProt (Q8PWY1) Pfam (PF01409) In PDB | Methanosarcina mazei | Pyrrolysine-tRNA ligase, PylRS |
| 2 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 10 | Chemie (EDO) | |||
| 3 | A | (2R)-2-AMINO-6-({[(2S,3R)-3-METHYLPYRROLIDIN-2-YL]CARBONYL}AMINO)HEXANOYL [(2S,3R,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL HYDROGEN (R)-PHOSPHATE | non-polymer | 586.5 | 1 | Chemie (YLY) | |||
| 4 | A | PYROPHOSPHATE 2- | non-polymer | 176.0 | 1 | Chemie (POP) | |||
| 5 | water | water | 18.0 | 186 | Chemie (HOH) |
Sequence modifications
A: 185 - 454 (UniProt: Q8PWY1)
| PDB | External Database | Details |
|---|---|---|
| Met 164 | - | cloning artifact |
| Gly 165 | - | cloning artifact |
| Ser 166 | - | cloning artifact |
| Ser 167 | - | cloning artifact |
| His 168 | - | expression tag |
| His 169 | - | expression tag |
| His 170 | - | expression tag |
| His 171 | - | expression tag |
| His 172 | - | expression tag |
| His 173 | - | expression tag |
| Ser 174 | - | cloning artifact |
| Ser 175 | - | cloning artifact |
| Gly 176 | - | cloning artifact |
| Leu 177 | - | cloning artifact |
| Val 178 | - | cloning artifact |
| Pro 179 | - | cloning artifact |
| Arg 180 | - | cloning artifact |
| Gly 181 | - | cloning artifact |
| Ser 182 | - | cloning artifact |
| His 183 | - | cloning artifact |
| Met 184 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33416.2 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1383.2 | |
| All* | Total formula weight | 34799.4 |
