2Q6J
Crystal Structure of Estrogen Receptor alpha Complexed to a B-N Substituted Ligand
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Estrogen receptor | polymer | 258 | 29386.6 | 2 | UniProt (P03372) Pfam (PF00104) | Homo sapiens (human) | ER, Estradiol receptor, ER-alpha |
| 2 | C, D (C, D) | GRIP peptide | polymer | 13 | 1579.9 | 2 | UniProt (Q8BN74) UniProt (by SIFTS) (Q61026) | Mus musculus (house mouse) | |
| 3 | E, F (A, B) | 4-[(DIMESITYLBORYL)(2,2,2-TRIFLUOROETHYL)AMINO]PHENOL | non-polymer | 439.3 | 2 | Chemie (A48) | |||
| 4 | G (B) | water | water | 18.0 | 1 | Chemie (HOH) |
Sequence modifications
A, B: 298 - 554 (UniProt: P03372)
| PDB | External Database | Details |
|---|---|---|
| Ser 297 | - | cloning artifact |
| Ser 537 | Tyr 537 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 61932.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 878.6 | |
| All* | Total formula weight | 62811.6 |
