2Q5G
Ligand binding domain of PPAR delta receptor in complex with a partial agonist
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Peroxisome proliferator-activated receptor delta | polymer | 283 | 32492.6 | 2 | UniProt (Q03181) Pfam (PF00104) | Homo sapiens (human) | PPAR-delta, PPAR- beta, Nuclear hormone receptor 1, NUC1, NUCI |
| 2 | C, D (A, B) | [(7-{[2-(3-MORPHOLIN-4-YLPROP-1-YN-1-YL)-6-{[4-(TRIFLUOROMETHYL)PHENYL]ETHYNYL}PYRIDIN-4-YL]THIO}-2,3-DIHYDRO-1H-INDEN- 4-YL)OXY]ACETIC ACID | non-polymer | 592.6 | 2 | Chemie (1FA) |
Sequence modifications
A, B: 201 - 477 (UniProt: Q03181)
| PDB | External Database | Details |
|---|---|---|
| His 195 | - | cloning artifact |
| His 196 | - | cloning artifact |
| His 197 | - | cloning artifact |
| His 198 | - | cloning artifact |
| His 199 | - | cloning artifact |
| His 200 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 64985.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1185.3 | |
| All* | Total formula weight | 66170.4 |
