2Q3Z
Transglutaminase 2 undergoes large conformational change upon activation
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Transglutaminase 2 | polymer | 687 | 77341.6 | 1 | UniProt (P21980) Pfam (PF00868) Pfam (PF01841) Pfam (PF00927) In PDB | Homo sapiens (human) | Tissue transglutaminase, TGase C, TGC, TGC, Transglutaminase-2, TGase- H |
2 | X | Polypeptide | polymer | 7 | 623.8 | 1 | |||
3 | A | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
4 | water | water | 18.0 | 262 | Chemie (HOH) |
Sequence modifications
A: 1 - 687 (UniProt: P21980)
PDB | External Database | Details |
---|---|---|
Gln 51 | Glu 51 | conflict |
Gln 186 | Glu 186 | conflict |
Gly 224 | Val 224 | conflict |
Thr 533 | Asn 533 | conflict |
Val 655 | Leu 655 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 77965.4 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 480.3 | |
All* | Total formula weight | 78445.7 |