2Q3Z
Transglutaminase 2 undergoes large conformational change upon activation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Transglutaminase 2 | polymer | 687 | 77341.6 | 1 | UniProt (P21980) Pfam (PF00868) Pfam (PF01841) Pfam (PF00927) | Homo sapiens (human) | Tissue transglutaminase, TGase C, TGC, TGC, Transglutaminase-2, TGase- H |
| 2 | B (X) | Polypeptide | polymer | 7 | 623.8 | 1 | |||
| 3 | C, D, E, F, G (A) | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 4 | H (A) | water | water | 18.0 | 262 | Chemie (HOH) |
Sequence modifications
A: 1 - 687 (UniProt: P21980)
| PDB | External Database | Details |
|---|---|---|
| Gln 51 | Glu 51 | conflict |
| Gln 186 | Glu 186 | conflict |
| Gly 224 | Val 224 | conflict |
| Thr 533 | Asn 533 | conflict |
| Val 655 | Leu 655 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 77965.4 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 480.3 | |
| All* | Total formula weight | 78445.7 |
